免 疫 原：HBeAg full length protein
SWISS：P0C573
Human Gene ID：HBV

Hepatitis B e-antigen (HBeAg) is a viral protein associated with HBV infections. Unlike the surface antigen, the e-antigen is found in the blood only when there are viruses also present. When the virus goes into “hiding,” the e-antigen will no longer be present in the blood. HBeAg is often used as a marker of ability to spread the virus to other people (infectivity). Measurement of e-antigen may also be used to monitor the effectiveness of HBV treatment; successful treatment will usually eliminate HBeAg from the blood and lead to development of antibodies against e-antigen (anti-HBe). There are some types (strains) of HBV that do not make e-antigen; these are especially common in the Middle East and Asia. In areas where these strains of HBV are common, testing for HBeAg is not very useful.
Function：May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells. This immune regulation may predispose to chronicity during pe
Subunit：Homodimerizes.
Subcellular Location：Secreted. Host nucleus.
Post-translational modifications：Phosphorylated.
Cleaved by host furin.
Similarity：Belongs to the orthohepadnavirus precore antigen family.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.