免 疫 原：KLH conjugated synthetic peptide derived from human ESM1
抗原表位：51-150/184
SWISS：Q9NQ30
Gene ID ：11082
Human Gene ID：11082

ESM1 is a secreted dermatan sulfate proteoglycan which is predominantly expressed in the endothelial cells in human lung and kidney tissues. Expression of ESM1 is regulated by cytokines. ESM1 may have a role in lung endothelial cell-leukocyte interactions. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.
Function：May have potent implications in lung endothelial cell-leukocyte interactions.
Subunit：Monomer.
Subcellular Location：Secreted. Peroxisome.
Tissue Specificity：Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney.
Post-translational modifications：May contain intrachain disulfide bonds.
Similarity：Contains 1 IGFBP N-terminal domain.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.