免 疫 原：KLH conjugated synthetic peptide derived from human Testicular H1 histone
抗原表位：51-207/207
SWISS：P22492
Gene ID ：3010
Human Gene ID：3010

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Function：Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
Subcellular Location：Nucleus. Chromosome.
Post-translational modifications：Phosphorylated in early spermatids.
Similarity：Belongs to the histone H1/H5 family.
Contains 1 H15 (linker histone H1/H5 globular) domain.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.