免 疫 原：KLH conjugated synthetic peptide derived from mouse GM-CSF
抗原表位：71-141/141
SWISS：P01587
Gene ID ：12981
Human Gene ID：1437

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008].
Function：Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
Subunit：Monomer. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits.
Subcellular Location：Secreted.
Similarity：Belongs to the GM-CSF family.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.