Rabbit Anti-Inhibin beta A antibody |
反应物种(预测) |
Rat |
产品应用(已验证) |
WB |
产品应用(可尝试) |
IHC,IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
研究领域 |
细胞生物,神经生物学,信号转导 |
标签 |
Array |
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Sample:ovary (Mouse) Lysate at 40 ug
Primary: Anti-Inhibin beta A (bs-1774R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 13/45kD
Observed band size: 40kD
RRID:AB_10856039
产品名称:Rabbit Anti-Inhibin beta A antibody
别名: Activin A; Activin beta A chain; Activin beta-A chain; ActivinA; EDF; Erythroid differentiation factor; Erythroid differentiation protein; INHBA; INHBA_HUMAN; Inhibin beta A chain.
中文名称:抑制素βA/Inhibin βA抗体
英文名称:Rabbit Anti-Inhibin beta A antibody
抗体来源: Rabbit
克隆类型:多克隆
细胞定位:分泌型蛋白
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原:KLH conjugated synthetic peptide derived from human Inhibin beta A
抗原表位:331-426/426
SWISS:P08476
Gene ID :3624
Human Gene ID:3624
The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome
Subunit:Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B. Activin A is a homodimer of beta-A. Activin B is a homodimer of beta-B. Activin AB is a dimer of beta-A and beta-B. Interac
Subcellular Location:Secreted.
Similarity:Belongs to the TGF-beta family.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.