Rabbit Anti-NALP3/CIAS1 antibody,蛋白Marker-蛋白检测试剂盒-IVD原料-北京博奥森生物技术有限公司

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Rabbit Anti-NALP3/CIAS1 antibody

多克隆 | SKU：bs-6655R

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货号:bs-3351R

￥1280

50μg

RMB1280

100μg

RMB1980

200μg

RMB2980

支持数据
产品信息
免疫原信息
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订购号:bs-6655R

￥1098.00-2900.00

50ul

100ul

200ul

货期：现货

售后保障

Rabbit Anti-NALP3/CIAS1 antibody
反应物种（预测）	Mouse
产品应用（可尝试）	WB,IHC,IF,ELISA
推荐稀释比例	WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,
研究领域	心血管,细胞生物,免疫学,信号转导,细胞凋亡
标签	Array

Sample:
Lung (Rat) Lysate at 40 ug
Colon carcinoma (Human) Lysate at 40 ug
Primary: Anti-NALP3/CIAS1 (bs-6655R) at 1/300 dilution
Secondary: HRP conjugated Goat-Anti-rabbit IgG (bs-0295G-HRP) at 1/5000 dilution
Predicted band size: 114 kD
Observed band size: 114 kD
Tissue/cell: Rat tracheal tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-Cryopyrin Polyclonal Antibody, Unconjugated(bs-3301R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

产品信息

RRID：AB_11102267
产品名称：Rabbit Anti-NALP3/CIAS1 antibody
别名： LRR and PYD domains-containing protein 3; AGTAVPRL; AII/AVP antibody Angiotensin/vasopressin receptor AII/AVP like; Angiotensin/vasopressin receptor AII/AVP-like; C1orf7; Caterpiller protein 1.1; CIAS 1; CIAS1; CLR1.1; Cold autoinflammatory syndrome 1; Co
中文名称：细胞凋亡诱导蛋白NALP3抗体
英文名称：Rabbit Anti-NALP3/CIAS1 antibody
抗体来源： Rabbit
克隆类型：多克隆
细胞定位：细胞浆
性状：Liquid
亚型：IgG
纯化方法：affinity purified by Protein A
保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

免疫原信息

免疫原：KLH conjugated synthetic peptide derived from human Cryopyrin
抗原表位：551-630/1036
SWISS：Q96P20
Gene ID ：114548
Human Gene ID：114548

产品介绍

May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.
Subcellular Location：Cytoplasm.
Tissue Specificity：Expressed in blood leukocytes. Strongly expressed in polymorphonuclear cells and osteoblasts. Undetectable or expressed at a lower magnitude in B- and T-lymphoblasts, respectively. High level of expression detected in chondrocytes. Detected in non-keratin
Similarity：Belongs to the NLRP family.
Contains 1 DAPIN domain.
Contains 9 LRR (leucine-rich) repeats.
Contains 1 NACHT domain.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.