Rabbit Anti-GPR84 antibody |
反应物种(预测) |
Rat,Dog,Cow,Horse,Sheep,Monkey |
产品应用(已验证) |
WB |
产品应用(可尝试) |
ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000, |
研究领域 |
细胞生物,神经生物学,信号转导,G蛋白偶联受体,G蛋白信号, |
标签 |
Array |
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Sample:
Lane 1: Blood cell (Mouse) Lysate at 40 ug
Lane 2: Lung (Mouse) Lysate at 40 ug
Lane 3: Bone (Rat) Lysate at 40 ug
Lane 4: Lung (Rat) Lysate at 40 ug
Lane 5: Cerebrum (Rat) Lysate at 40 ug
Lane 6: Cerebellum (Rat) Lysate at 40 ug
Lane 7: U937 (Human) Cell Lysate at 30 ug
Lane 8: U87MG (Human) Cell Lysate at 30 ug
Lane 9: THP-1 (Human) Cell Lysate at 30 ug
Primary: Anti-GPR84 (bs-13507R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 44 kD
Observed band size: 44 kD
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Sample:
SP2/0 (mouse)Cell Lysate at 40 ug
Lung(mouse) Lysate at 40 ug
HL-60 (human)Cell Lysate at 40 ug
Muscle (mouse) Lysate at 40 ug
Primary: Anti- GPR84 (bs-13507R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 44kD
Observed band size: 44 kD
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Sample: bone (Rat) Lysate at 40 ug
Primary: Anti- GPR84 (bs-13507R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 44kD
Observed band size: 44 kD
RRID:RRID
产品名称:Rabbit Anti-GPR84 antibody
别名: G protein coupled receptor 84; G-protein coupled receptor 84; G protein coupled receptor EX33; GPCR 4; GPCR4; GPR 84; GPR84_HUMAN; GPR84 (EX33); EX33; Inflammation related G protein coupled receptor EX33; Inflammation-related G-protein coupled receptor EX
中文名称:G蛋白偶联受体84抗体
英文名称:Rabbit Anti-GPR84 antibody
抗体来源: Rabbit
克隆类型:多克隆
细胞定位:细胞膜
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原:KLH conjugated synthetic peptide derived from human GPCR EX33/GPR84
抗原表位:1-100/396
抗原细胞定位:Extracellular
SWISS:Q9NQS5
Gene ID :53831
Human Gene ID:53831
G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 84 (GPR84), a member of the GCPR 1 family, is an orphan GCPR expressed in bone marrow, brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta, intestine, lung and peripheral blood leukocytes. In activated T cells, GPR84 regulates early interleukin-4 (IL-4) gene expression.
Function:Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturate
Subcellular Location:Cell membrane.
Tissue Specificity:Expressed predominantly in hematopoietic tissues. High levels detected in the bone marrow and lower levels in the peripheral leukocytes and lung. Also expressed in brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta and intestine. Within
Similarity:Belongs to the G-protein coupled receptor 1 family.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.