| Rabbit Anti-ADCY10 antibody |
| 反应物种（预测） |
Mouse,Dog,Pig,Cow,Horse,Rabbit |
| 产品应用（已验证） |
WB,IF |
| 产品应用（可尝试） |
IHC,ELISA |
| 推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:200, |
| 研究领域 |
肿瘤,免疫学,细胞凋亡,转录调节因子,激酶和磷酸酶 |
| 标签 |
Array |
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Tissue/cell: rat brain tissue;4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-ADCY10 Polyclonal Antibody, Unconjugated(bs-3916R) 1:200, overnight at 4°C; The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated(bs-0295G-Cy3)used at 1:200 dilution for 40 minutes at 37°C. DAPI(5ug/ml,blue,C-0033) was used to stain the cell nuclei
RRID：AB_10857435
产品名称：Rabbit Anti-ADCY10 antibody
别名： Adenylate cyclase 10; Adenylate cyclase homolog; AH related protein; ATP pyrophosphate-lyase; Germ cell soluble adenylyl cyclase; HCA2; hsAC; hypercalciuria absorptive; SAC; SACI; Sacy; Soluble adenylyl cyclase; Testicular soluble adenylyl cyclase; 3',5'-
中文名称：腺苷酸环化酶10抗体
英文名称：Rabbit Anti-ADCY10 antibody
抗体来源： Rabbit
克隆类型：多克隆
细胞定位：细胞浆,细胞膜
性 状：Liquid
亚 型：IgG
纯化方法：affinity purified by Protein A
保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原：KLH conjugated synthetic peptide derived from human ADCY10
抗原表位：1101-1200/1610
SWISS：Q96PN6
Gene ID ：55811
Human Gene ID：55811
ADCY10 belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction.
Subcellular Location：Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Note: Distributed to subcellular compartments containing cAMP targets. Found as a plasma membrane associated protein, protein concentrate
Tissue Specificity：Weakly expressed in multiple tissues. Expressed in brain, heart, kidney, liver, lung, pancreas, peripheral blood leukocytes, placenta, skeletal muscle, stomach, thymus, airway epithelial cells, duodenum, jejunum and ileum. Very low level of expression in
Similarity：Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Contains 2 guanylate cyclase domains.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
400-901-9800
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