免 疫 原：KLH conjugated Synthesised phosphopeptide derived from human PIK3C3 around the phosphorylation site of Ser282
抗原表位：GP(p-S)DH
SWISS：Q8NEB9
Gene ID ：5289
Human Gene ID：5289

PI 3 Kinase Class 3 is a member of the PI3/PI4-kinase family. It is the catalytic subunit of the PI3K complex. It is involved in the transport of lysosomal enzyme precursors to lysosomes. It is ubiquitously expressed, with a highest expression in skeletal muscle.
Function：Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for th
Subunit：Heterodimer. This subunit, part of a complex composed of regulatory and catalytic subunits, associates with regulatory subunit PIK3R4. Forms a complex with BECN1, PIK3R4 and either UVRAG and KIAA0226/Rubicon, or with ATG14. In this complex, presence of UV
Subcellular Location：Midbody. Late endosome.
Tissue Specificity：Ubiquitously expressed, with a highest expression in skeletal muscle.
Similarity：Belongs to the PI3/PI4-kinase family.
Contains 1 C2 PI3K-type domain.
Contains 1 PI3K/PI4K domain.
Contains 1 PIK helical domain.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.