Rabbit Anti-HDGF antibody |
反应物种(预测) |
Mouse,Rat,Pig,Cow,GuineaPig |
产品应用(已验证) |
IHC |
产品应用(可尝试) |
ICC,IF,ELISA |
推荐稀释比例 |
Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
研究领域 |
肿瘤,细胞生物,免疫学,肿瘤细胞生物标志物, |
标签 |
Array |
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Paraformaldehyde-fixed, paraffin embedded (human gastric carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (HDGF) Polyclonal Antibody, Unconjugated (bs-10956R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
RRID:RRID
产品名称:Rabbit Anti-HDGF antibody
别名: HDGF; HDGF_HUMAN; Hepatoma derived growth factor; Hepatoma-derived growth factor; High mobility group protein 1 like 2; High mobility group protein 1-like 2; HMG-1L2; HMG1L2.
中文名称:肝癌衍生生长因子/高迁移率族蛋白1样蛋白2抗体
英文名称:Rabbit Anti-HDGF antibody
抗体来源: Rabbit
克隆类型:多克隆
细胞定位:细胞浆,细胞膜
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原:KLH conjugated synthetic peptide derived from human HDGF
抗原表位:81-180/240
SWISS:P51858
Gene ID :3068
Human Gene ID:3068
This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. This gene was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Function:Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor.
Subunit:Monomer, and domain-swapped homodimer.
Subcellular Location:Cytoplasm. Nucleus.
Tissue Specificity:Ubiquitous.
Post-translational modifications:Sumoylated by SUMO1. Sumoylation prevents binding to chromatin.
Similarity:Belongs to the HDGF family.
Contains 1 PWWP domain.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.