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Rabbit Anti-Caspase-6 subunit p11 antibody
多克隆  |   SKU:bs-10135R

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货号:bs-3351R
¥1280
订购号:bs-10135R
¥1138.00-2900.00
货期:现货
Rabbit Anti-Caspase-6 subunit p11 antibody
反应物种(预测)

Dog,Pig,Cow

产品应用(已验证)

WB,IHC

产品应用(可尝试)

ICC,IF,ELISA

推荐稀释比例

WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500,

研究领域

细胞生物,神经生物学,信号转导

标签

Array

  • Paraformaldehyde-fixed, paraffin embedded (rat brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Caspase-6 subunit p11) Polyclonal Antibody, Unconjugated (bs-10135R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
  • Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Caspase-6 subunit p11) Polyclonal Antibody, Unconjugated (bs-10135R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
  • Sample:
    Cerebrum (Rat) Lysate at 40 ug
    Primary: Anti- Caspase-6 subunit p11 (bs-10135R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 11/33 kD
    Observed band size: 33 kD

产品信息

RRID:RRID
产品名称:Rabbit Anti-Caspase-6 subunit p11 antibody
别名: Caspase-6 subunit p11; Caspase-6 p11; Apoptosis Related Cysteine Protease; Apoptotic cysteine protease MCH2; Apoptotic protease MCH 2; Apoptotic protease MCH2; Casp 6; Casp6; Caspase 6 apoptosis related cysteine protease; Caspase 6 precursor; Caspase6; Hu
中文名称:半胱胺酸蛋白酶蛋白-6抗体
英文名称:Rabbit Anti-Caspase-6 subunit p11 antibody
抗体来源: Rabbit
克隆类型:多克隆
细胞定位:细胞浆
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

免疫原信息

免 疫 原:KLH conjugated synthetic peptide derived from human Caspase-6 subunit p11
抗原表位:181-293/293
SWISS:P55212
Gene ID :839
Human Gene ID:839

产品介绍

Caspase-6 Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. Subunit is compose of heterodimer of a18 kDa (p18) and a 11 kDa (p11) subunit. Subcellular location at cytoplasmic. Cleavages by CPP32, caspase-8 or -10 generate the two active subunits. It belongs to the peptidase C14 family.
Function:Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
Subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (p18) and a 11 kDa (p11) subunit. Interacts with BIRC6/bruce.
Subcellular Location:Cytoplasm.
Post-translational modifications:Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.
Similarity:Belongs to the peptidase C14A family.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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