Rabbit Anti-EV71 polyprotein 3D antibody |
反应物种(预测) |
EV71 |
产品应用(已验证) |
WB |
产品应用(可尝试) |
ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000, |
研究领域 |
细胞生物,免疫学,细菌及病毒, |
标签 |
Array |
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Sample:
EV71 polyprotein 3D Protein Overexpression E.coli Lysate (Cat#: bs-49067P) at 4 ug
Primary: Anti-EV71 polyprotein 3D (bs-2339R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 56 kD
Observed band size: 56 kD
RRID:RRID
产品名称:Rabbit Anti-EV71 polyprotein 3D antibody
别名: 3D polymerase; Human enterovirus 71 polyprotein 3D; EV71; Enterovirus 71; EV71 3D.
中文名称:肠道病毒71型/手足口病病毒3D抗体
英文名称:Rabbit Anti-EV71 polyprotein 3D antibody
抗体来源: Rabbit
克隆类型:多克隆
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原:KLH conjugated synthetic peptide derived from EV71 polyprotein 3D
抗原表位:2101-2193/2193
SWISS:Q66478
Human Gene ID:EV71
Enteroviruses, such as enterovirus 71, are classified to be in the picornavirus family, pico [small] + RNA [ribonucleic acid] + virus. Picornaviruses are among the smallest and simplest ribonucleic acid containing viruses known (1). The RNA for many enteroviruses have now been cloned and complete genomic sequences have been obtained. The RNA from all sequenced enteroviruses are similar in length, about 7400 nucleotides, and have identical organization (1).
The human alimentary tract is the predominant site of enterovirus replication and these viruses were first isolated from enteric specimens. These viruses are the cause of paralytic poliomyelitis, aseptic meningitis-encephalitis, myocarditis, pleurodynia, hand-foot-and-mouth disease, conjunctivitis, and numerous other syndromes associated with extra-intestinal target organs. There are 67 numbered types of enteroviruses in the enterovirus family (1): three polioviruses, twenty-three coxsackieviruses A, six coxsackieviruses B, thirty-one echoviruses, and four other enteroviruses.
Function:Protein VP1: Forms, together with VP2 and VP3, an icosahedral capsid (pseudo T=3), 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome. Protein VP1 mainly forms the vertices of the cap
Subunit:Protein 2C N-terminus interacts with human RTN3. This interaction is important for viral replication.
Subcellular Location:Protein VP2: Virion. Host cytoplasm (Potential).
Protein VP3: Virion. Host cytoplasm (Potential).
Protein VP1: Virion. Host cytoplasm (Potential).
Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Po
Post-translational modifications:Specific enzymatic cleavages in vivo by the viral proteases yield a variety of precursors and mature proteins. Polyprotein processing intermediates such as VP0 which is a VP4-VP2 precursor are produced. During virion maturation, non-infectious particles a
Similarity:Belongs to the picornaviruses polyprotein family.
Contains 2 peptidase C3 domains.
Contains 1 RdRp catalytic domain.
Contains 1 SF3 helicase domain.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.