免 疫 原：KLH conjugated synthetic peptide derived from human COQ10B
抗原表位：38-110/238
SWISS：Q9H8M1
Gene ID ：80219
Human Gene ID：80219

COQ10B, Coenzyme Q10, is a 247 amino acid protein encoded by the human gene COQ10B. COQ10B is a mitochondrial protein that belongs to the COQ10 family. COQ10B is an essential biological cofactor which increases brain mitochondrial concentration and exerts neuroprotective effects. Plasma COQ10B levels decrease in patients with advanced chronic heart failure (CHF) while COQ10B levels in hyperthyroid patients are found among the lowest detected in human diseases. Likewise, COQ10B is elevated in hypothyroid subjects, also in subclinical conditions, suggesting the usefulness of this index in assessing metabolic status in thyroid disorders. It is believed that secretion of adrenal hormones is in some way related to COQ10B levels, both in augmented and reduced conditions. However, since thyroid hormones have an important role in modulating COQ10B levels and metabolism, when coexistent, thyroid deficiency seems to play a prevalent role in comparison with adrenal deficiency.
Function：COQ10 (Coenzyme Q10) is found in a wide variety of foods and is synthesized in all tissues. The de novo biosynthesis of COQ10, from its precursor tyrosine, is a multistage process that requires at least eight vitamins and several trace elements. More comp
Subunit：Interacts with coenzyme Q
Subcellular Location：Mitochondrion inner membrane; Peripheral membrane protein; Matrix side
Similarity：Belongs to the COQ10 family.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.