免 疫 原：KLH conjugated synthetic peptide derived from human MON1A
抗原表位：51-150/555
SWISS：Q86VX9
Gene ID ：84315
Human Gene ID：84315

MON1A is a 555 amino acid protein that exists as multiple alternatively spliced isoforms and plays an important role in membrane trafficking, specifically through the secretory apparatus. The gene encoding MON1A maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Function：Plays an important in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes.
Similarity：Belongs to the MON1/SAND family.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.