| Rabbit Anti-SAPS1 antibody |
| 反应物种（预测） |
Dog,Pig,Cow,Horse,Rabbit,Rhesus monkey, Gorilla, Orangutan |
| 产品应用（已验证） |
WB |
| 推荐稀释比例 |
WB=1:500-2000, |
| 研究领域 |
细胞生物,信号转导,激酶和磷酸酶 |
| 标签 |
Array |
-
Sample:
Lane 1: Stomach (Mouse) Lysate at 40 ug
Lane 2: Testis (Mouse) Lysate at 40 ug
Lane 3: Lymph node (Mouse) Lysate at 40 ug
Lane 4: Testis (Rat) Lysate at 40 ug
Lane 5: HL60 (Human) Cell Lysate at 30 ug
Lane 6: 293T (Human) Cell Lysate at 30 ug
Lane 7: Molt-4 (Human) Cell Lysate at 30 ug
Primary: Anti-SAPS1 (bs-19388R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 120 kD
Observed band size: 120 kD
RRID：RRID
产品名称：Rabbit Anti-SAPS1 antibody
别名： PP6R1;
Protein phosphatase 6, regulatory subunit 1;
SAP190;
SAPS domain family, member 1.
中文名称：SAPS结构域家族1抗体
英文名称：Rabbit Anti-SAPS1 antibody
抗体来源： Rabbit
克隆类型：多克隆
细胞定位：细胞浆
性 状：Liquid
亚 型：IgG
纯化方法：affinity purified by Protein A
保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原：KLH conjugated synthetic peptide derived from human SAPS1
抗原表位：31-130/881
SWISS：Q9UPN7
Gene ID ：22870
Human Gene ID：22870
Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010]
Function：Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha.
Subunit：Protein phosphatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed of the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS). Interacts with PPP6C and NFKBIE. I
Subcellular Location：Cytoplasm
Tissue Specificity：Ubiquitous with higher expression in testis.
Similarity：Belongs to the SAPS family.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
400-901-9800
说明书
联系我们
打印此页面
收藏