| Rabbit Anti-IDO1 antibody |
| 产品应用（已验证） |
WB |
| 产品应用（可尝试） |
IHC,IF,ELISA |
| 推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
| 研究领域 |
肿瘤,心血管,细胞生物,免疫学,信号转导,新陈代谢, |
| 标签 |
Array |
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Sample:
Lane 1: Mouse Epididymis tissue lysates
Lane 2: Human Hela cell lysates
Lane 3: Human Molt-4 cell lysates
Primary: Anti-IDO (bs-23751R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 45 kD
Observed band size: 48 kD
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Sample:
Lane 1: Mouse Placenta tissue lysates
Lane 2: Mouse Spleen tissue lysates
Lane 3: Mouse Lung tissue lysates
Lane 4: Rat Lymph node tissue lysates
Lane 5: Human Huvec cell lysates
Lane 6: Human Hela cell lysates
Lane 7: Human A431 cell lysates
Primary: Anti-IDO (bs-23751R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 45 kD
Observed band size: 47 kD
RRID：RRID
产品名称：Rabbit Anti-IDO1 antibody
别名： Indoleamine 2, 3-dioxygenase ; 3-dioxygenase; I23O1_HUMAN; IDO 1; IDO; IDO-1; INDO; indolamine 2,3 dioxygenase; Indole 2 3 dioxygenase; indoleamine 2 3 dioxygenase 1; indoleamine 2 3 dioxygenase; Indoleamine 2,3-dioxygenase 1; Indoleamine pyrrole 2 3 diox
中文名称：吲哚胺2,3-双加氧酶抗体
英文名称：Rabbit Anti-IDO1 antibody
抗体来源： Rabbit
克隆类型：多克隆
细胞定位：细胞浆
性 状：Liquid
亚 型：IgG
纯化方法：affinity purified by Protein A
保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原：KLH conjugated synthetic peptide derived from mouse IDO1
抗原表位：251-350/403
SWISS：P28776
Gene ID ：15930
Human Gene ID：3620
This gene encodes indoleamine 2,3-dioxygenase (IDO) – a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.
Function：Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.
Similarity：Belongs to the indoleamine 2,3-dioxygenase family.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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