| Rabbit Anti-5-HTR3 antibody |
| 反应物种（预测） |
Human,Dog,Horse |
| 产品应用（已验证） |
WB |
| 产品应用（可尝试） |
ELISA |
| 推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000, |
| 研究领域 |
神经生物学,通道蛋白,细胞膜受体 |
| 标签 |
Array |
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Sample:
Lane 1: Cerebellum (Mouse) Tissue Lysate at 40 ug
Lane 2: Stomach (Mouse) TissueLysate at 40 ug
Lane 3: Cerebellum (Rat) Tissue Lysate at 40 ug
Lane 4: Spinal cord (Rat) Tissue Lysate at 40 ug
Primary: Anti-5-HTR3 (bs-24700R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 53 kD
Observed band size: 50 kD
RRID：RRID
产品名称：Rabbit Anti-5-HTR3 antibody
别名： 5 HT 3; 5 HT3; 5 HT3A; HTR-3A; 5 HT3A receptor; 5 HT3R; 5 HT3RA; 5 hydroxytryptamine (serotonin) receptor 3A; 5 Hydroxytryptamine receptor 3; 5-HT-3; 5-HT3-A; 5-HT3A; 5-HT3R; 5-hydroxytryptamine receptor 3; 5-hydroxytryptamine receptor 3A; 5HT 3; 5HT 3A;
中文名称：5-羟色胺受体3抗体
英文名称：Rabbit Anti-5-HTR3 antibody
抗体来源： Rabbit
克隆类型：多克隆
细胞定位：细胞膜
性 状：Liquid
亚 型：IgG
纯化方法：affinity purified by Protein A
保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原：KLH conjugated synthetic peptide derived from human 5-HTR3
抗原表位：24-120/478
抗原细胞定位：Extracellular
SWISS：P46098
Gene ID ：3359
Human Gene ID：3359
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta. Belongs to the ligand-gated ionic channel (TC 1.A.9) family.
Function：This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phospha
Subunit：Forms pentahomomeric complex as well as pentaheteromeric complex with HTR3B or HTR3C or HTR3D or HTR3E; homomeric complex is functional but exhibits low conductance with modified voltage dependence, and decreased agonist and antagonist affinity. Interacts
Subcellular Location：Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Tissue Specificity：Expressed in brain. Higher levels of expression are observed in the cerebellum, occipital cortex and frontal cortex.
Similarity：Belongs to the G-protein coupled receptor 1 family.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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