Rabbit Anti-KIF5B antibody |
反应物种(预测) |
Mouse,Rat,Chicken,Pig,Cow,Horse,Rabbit,Sheep |
产品应用(已验证) |
IHC |
产品应用(可尝试) |
ELISA |
推荐稀释比例 |
Elisa=1:5000-10000,IHC-P=1:400-800, |
研究领域 |
神经生物学,信号转导,细胞粘附分子,细胞骨架, |
标签 |
Array |
-
Paraformaldehyde-fixed, paraffin embedded (Human kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (KIF5B) Polyclonal Antibody, Unconjugated (bs-24717R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
RRID:RRID
产品名称:Rabbit Anti-KIF5B antibody
别名: Conventional kinesin heavy chain; KIF5B; Kinesin 1 (110-120kD); Kinesin family member 5B; Kinesin heavy chain; Kinesin heavy chain ubiquitous; Kinesin-1 heavy chain; KINH; KINH_HUMAN; KNS 1; KNS; KNS1; Ubiquitous kinesin heavy chain; UKHC.
中文名称:驱动蛋白KNS1抗体
英文名称:Rabbit Anti-KIF5B antibody
抗体来源: Rabbit
克隆类型:多克隆
细胞定位:细胞浆
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原:KLH conjugated synthetic peptide derived from human KIF5B
SWISS:P33176
Gene ID :3799
Human Gene ID:3799
Structural proteins in Arabidopsis provide cellular stability, facilitate protein transportation within the cell and are essential for cell growth. Three types of molecular motors are involved in the organization, dynamics and transport processes associated with the cytoskeleton (1). They include myosin, which transports cargo along actin filaments, and kinesin and dynein, which transport cargo along microtubules (1,2). These proteins regulate many cellular functions, including cell division and expansion, cell-to-cell communication, membrane trafficking and morphogenesis (2). In addition, the dynamin-like proteins are GTP-binding proteins involved in vesicle trafficking (3). Extensin is a structural protein that may be involved in cell wall assembly, while expansin is a cell wall loosening protein that induces stress relaxation and extension of cell walls and may control organ size, morphology and abscission (4,5). Also, xyloglucan (XG), a major hemicellulose in plants, is modified by the fucosyltransferase, XG FTase, which adds a terminal fucosyl residue to XG (6).
Function:Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.
Subunit:Oligomer composed of two heavy chains and two light chains. Interacts with GRIP1 and PPP1R42 (By similarity). Interacts with SYBU. Interacts with JAKMIP1. Interacts with PLEKHM2. Interacts with ECM29.
Subcellular Location:Cytoplasm, cytoskeleton. Note=Uniformly distributed between soma and neurites in hippocampal neurons.
Similarity:Belongs to the kinesin-like protein family. Kinesin subfamily.
Contains 1 kinesin-motor domain.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.