免 疫 原：KLH conjugated synthetic peptide derived from human PAX1
抗原表位：181-280/534
SWISS：P15863
Gene ID ：5075
Human Gene ID：5075

This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations. [provided by RefSeq, Mar 2012]
Function：This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column.
Subcellular Location：Nucleus.
Similarity：Contains 1 paired domain.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.