免 疫 原：KLH conjugated synthetic peptide derived from human WNT7A
抗原表位：201-300/349
SWISS：O00755
Gene ID ：7476
Human Gene ID：7476

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts.
Function：Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts (By similarity).
Subunit：Interacts with PORCN.
Subcellular Location：Secreted, extracellular space, extracellular matrix.
Tissue Specificity：Expression is restricted to placenta, kidney, testis, uterus, fetal lung, and fetal and adult brain.
DISEASE：Defects in WNT7A are the cause of limb pelvis hypoplasia aplasia syndrome (LPHAS) [MIM:276820]. A syndrome of severe deficiency of the extremities due to hypo- or aplasia of one or more long bones of one or more limbs. Pelvic manifestations include hip di
Similarity：Belongs to the Wnt family.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.