Mouse Anti-Human PD-L1 antibody |
产品应用(已验证) |
WB,FCM |
推荐稀释比例 |
WB=1:500-2000,Flow Cyt=2ug/Test, |
研究领域 |
肿瘤,细胞生物,信号转导,细胞凋亡 |
标签 |
Array |
RRID:RRID
产品名称:Mouse Anti-Human PD-L1 antibody
别名: Programmed cell death 1 ligand 1; CD274; B7 H; B7 H1; B7 homolog 1; B7-H1; B7H; B7H1; CD 274; CD274 antigen; CD274 molecule; MGC142294; MGC142296; OTTHUMP00000021029; PD L1; PD1L1_HUMAN; PD1L1_Mouse; PDCD1 ligand 1; PDCD1L1; PDCD1LG1; PDL 1; PDL1; Program
中文名称:人程序性死亡配体1单克隆抗体
英文名称:Mouse Anti-Human PD-L1 antibody
抗体来源: Mouse
克隆类型:单克隆
细胞定位:细胞膜
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原:Recombinant human PD-L1 protein
抗原表位:15-239/290
SWISS:Q9NZQ7
Gene ID :29126
Human Gene ID:29126
This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.