Rabbit Anti-Phospho-PTPN11 (Tyr511) antibody |
反应物种(预测) |
Mouse,Rat,Chicken,Pig,Cow,Rabbit,Zebrafish,Sheep |
产品应用(已验证) |
IHC |
产品应用(可尝试) |
ELISA |
推荐稀释比例 |
Elisa=1:5000-10000,IHC-P=1:400-800, |
研究领域 |
肿瘤,免疫学,神经生物学,信号转导,激酶和磷酸酶 |
标签 |
Array |
RRID:RRID
产品名称:Rabbit Anti-Phospho-PTPN11 (Tyr511) antibody
别名: PTPN11(phospho Y511); SHIP2; BPTP 3; BPTP3; CFC; MGC14433; Noonan syndrome 1; Noonan syndrome 1 protein tyrosine phosphatase 2C; NS 1; NS1; Protein tyrosine phosphatase 2C; Protein Tyrosine Phosphatase Non receptor Type 11; PTP 1D; PTP 2C; PTP1D; PTP2C; P
中文名称:磷酸化蛋白酪氨酸磷酸酶2抗体
英文名称:Rabbit Anti-Phospho-PTPN11 (Tyr511) antibody
抗体来源: Rabbit
克隆类型:多克隆
细胞定位:细胞浆
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原:KLH conjugated Synthesised phosphopeptide derived from human PTPN11 around the phosphorylation site of Tyr511
抗原表位:AQ(p-Y)RF
SWISS:Q06124
Gene ID :5781
Human Gene ID:5781
The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs). Several groups have independently identified a non transmembrane PTP, designated SHPTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N terminal to the PTP domain. A second and much more widely expressed PTP with SH2 domains, SHPTP2 (also designated PTP1D and Syp), has been identified. SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.