Rabbit Anti-CD36 antibody |
反应物种(预测) |
Dog,Pig,Cow,Horse |
产品应用(已验证) |
WB |
产品应用(可尝试) |
IHC,IF,ELISA |
推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
研究领域 |
肿瘤,心血管,细胞生物,免疫学,干细胞,细胞膜受体,细胞类型标志物(Endothelial Markers),血管内皮细胞,内皮细胞, |
标签 |
Array |
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Tissue/cell: rat heart tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-CD36/PAS-4 Polyclonal Antibody, Unconjugated(bs-1100R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
RRID:AB_10857200
产品名称:Rabbit Anti-CD36 antibody
别名: Platelet glycoprotein 4; PAS-4; Platelet glycoprotein IV; Glycoprotein IIIb; GPIV; GPIIIB; GP3B; Leukocyte differentiation antigen CD36; PAS IV; Platelet collagen receptor; Fatty acid translocase; FAT; Thrombospondin receptor; CD_antigen: GP4; CD36_HUMAN.
中文名称:CD36抗体
英文名称:Rabbit Anti-CD36 antibody
抗体来源: Rabbit
克隆类型:多克隆
细胞定位:细胞膜
性 状:Liquid
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原:KLH conjugated synthetic peptide derived from mouse CD36
抗原表位:51-150/472
抗原细胞定位:Extracellular
SWISS:Q08857
Gene ID :12491
Human Gene ID:948
The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]
Function:Seems to have numerous potential physiological functions. Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocyte
Subunit:Interacts with THBS1 and THBS2; the interactions mediate the THBS antiangiogenic activity.
Subcellular Location:Membrane; Multi-pass membrane protein.
Tissue Specificity:Predominant in heart, intestine, spleen, fat, skeletal muscle, lower in testes.
Post-translational modifications:N-glycosylated and O-glycosylated with a ratio of 2:1.
DISEASE:Defects in CD36 are the cause of platelet glycoprotein IV deficiency (PG4D)[MIM:608404]; also known as CD36 deficiency. Platelet glycoprotein IV deficiency can be divided into 2 subgroups. The type I phenotype is characterized by platelets and monocytes/m
Similarity:Belongs to the CD36 family.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.