| Rabbit Anti-Integrin Alpha V + Beta 1 antibody |
| 反应物种（预测） |
Mouse,Dog,Pig,Cow,Horse,Sheep |
| 产品应用（已验证） |
WB,FCM |
| 产品应用（可尝试） |
IHC,ELISA |
| 推荐稀释比例 |
WB=1:500-2000,Elisa=1:5000-10000,IHC-P=1:100-500,Flow Cyt=1μg /test, |
| 研究领域 |
细胞生物,信号转导,细胞膜受体,细胞粘附分子, |
| 标签 |
Array |
-
Sample:
Lane 1: A549 (Human) Cell Lysate at 30 ug
Lane 2: U251 (Human) Cell Lysate at 30 ug
Lane 3: Huvec (Human) Cell Lysate at 30 ug
Lane 4: SH-SY5Y (Human) Cell Lysate at 30 ug
Lane 5: U2os (Human) Cell Lysate at 30 ug
Lane 6: MCF-7 (Human) Cell Lysate at 30 ug
Lane 7: Jurkat (Human) Cell Lysate at 30 ug
Primary: Anti-Integrin Alpha V + Beta 1 (bs-2016R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 125 kD
Observed band size: 125 kD
-
Blank control (blue line): MCF7 (fixed with 70% methanol overnight at 4℃).
Primary Antibody (green line): Rabbit Anti-Integrin Alpha V + Beta 1 antibody (bs-2016R), Dilution: 1μg /10^6 cells;
Isotype Control Antibody (orange line): Rabbit IgG .
Secondary Antibody (white blue line): Goat anti-rabbit IgG-PE, Dilution: 1μg /test.
RRID：AB_10857270
产品名称：Rabbit Anti-Integrin Alpha V + Beta 1 antibody
别名： Integrin alpha 5 beta 1; fibronectin receptor alpha; ITGAV; CD51; DKFZp686A08142; MSK8; Msk 8; VNR; similar to Integrin alpha-V precursor; Vitronectin receptor subunit alpha; CD51 antigen; HGNC; Vitronectin receptor alpha polypeptide; Vitronectin receptor
中文名称：整合素αVβ1抗体
英文名称：Rabbit Anti-Integrin Alpha V + Beta 1 antibody
抗体来源： Rabbit
克隆类型：多克隆
细胞定位：细胞浆,分泌型蛋白
性 状：Liquid
亚 型：IgG
纯化方法：affinity purified by Protein A
保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
免 疫 原：KLH conjugated synthetic Mixed peptides 915-948/1048(human Integrin αV)+ 21-70/798(human Integrin β1)
SWISS：P06756
Gene ID ：3685
Human Gene ID：3685
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells.
Integrin alpha 5 belongs to the integrin alpha chain family. It contains seven FG-GAP repeats.
Integrin beta 1 belongs to the integrin beta chain family. It contains one VWFA domain.
Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein se
ems to enhance angiogenesis in Kaposi's sarcoma lesions.
Function：The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In
Subcellular Location：Membrane.
Similarity：Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
400-901-9800
说明书
联系我们
打印此页面
收藏