Mouse Anti-human CD33-APC antibody,蛋白Marker-蛋白检测试剂盒-IVD原料-北京博奥森生物技术有限公司

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Mouse Anti-human CD33-APC antibody

单克隆 | CloneNo.: HI33a | SKU：bsm-30078M-APC

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货号:bs-3351R

￥1280

50μg

RMB1280

100μg

RMB1980

200μg

RMB2980

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订购号:bsm-30078M-APC

￥1880.00-2980.00

50T

100T

货期：现货

售后保障

Mouse Anti-human CD33-APC antibody
产品应用（已验证）	FCM
推荐稀释比例	Flow Cyt=5ul/Test,
研究领域	免疫学,干细胞,细胞表面分子,
标签	Array

Flow cytometry staining of normal human peripheral blood cells with CD33/APC(bsm-30078M-APC)(Red histogram) or Mouse IgG2a Isotype Control (APC Conjugate)(C03-12004)(Blue histogram) . Total cells were used for analysis.
Blank control:U-937.
Primary Antibody (green line): Rabbit Anti-CD33 antibody (bsm-30078M-APC)
Dilution: 1ug/Test;
Protocol
The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature.Acquisition of 20,000 events was performed.

产品信息

RRID：RRID
产品名称：Mouse Anti-human CD33-APC antibody
别名： CD33_HUMAN; CD 33; CD33 antigen; CD33 molecule; FLJ00391; gp67 ; Myeloid cell surface antigen CD33; Myeloid cell surface antigen CD33 precursor; p67 ; Sialic acid binding Ig like lectin 3; Sialic acid binding immunoglobulin like lectin 3; SIGLEC3; Siglec-
中文名称：APC标记人CD33单克隆抗体
英文名称：Mouse Anti-human CD33-APC antibody
中文别名：APC anti-human CD33;
抗体来源： Mouse
克隆类型：单克隆
细胞定位：细胞膜
性状：Liquid
亚型：IgG2a
纯化方法：affinity purified by Protein G
保存条件：Store at 2-8℃ for one year. Avoid repeated freeze/thaw cycles.

SWISS：P20138
Gene ID ：945
Human Gene ID：945

产品介绍

CD33 is found on granulocyte and macrophage precursors in the bone marrow, but is not on pluripotent stem cells. The protein is also expressed on, and is a useful marker for, peripheral monocytes. It is also useful for distinguishing myelogenous leukaemia cells from lymphoid or erythroid leukaemias.
Function：Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on
Subunit：Interacts with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation.
Subcellular Location：Cell membrane; Single-pass type I membrane protein.
Tissue Specificity：Monocytic/myeloid lineage cells.
Post-translational modifications：Phosphorylation of Tyr-340 is involved in binding to PTPN6 and PTPN11.
Phosphorylation of Tyr-358 is involved in binding to PTPN6.
Similarity：Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Important Note：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.